Over the past two decades, AES has created a full complement of laminar flow systems and custom products, engineered to meet the most demanding conditions, day after day, inside critical manufacturing environments.

Send us your specification, and we will provide a custom solution.

Case Study #1

An aseptic production facility was found to be out of compliance with regard to transport of stoppered vials that traveled to a remote area for lyophilization. Instead of upgrading the facility to meet the stringent cleanliness requirements, which would have required a significant shutdown of the facility for renovations and new mechanical systems, AES designed and built a customized class 100 transport cart that was used to provide a mobile critical environment. This custom product allowed the facility to meet cGMP’s for product protection, without the need for costly facility upgrades.

Case Study #2

A weigh-dispense operation was determined to lack proper product protection in terms of contamination control. On a fast-track product installation, AES designed and fabricated a customized weigh-dispense booth that was configured to fit into less-than-ideal existing building conditions so that the surrounding warehouse area could remain undisturbed. The booth was created to surround an existing building column to minimize the overall footprint lost within the building. This product featured laminar flow module technology to create the environmental conditions for clean-containment of the powders that were being dispensed. In addition, a multi-purpose airlock was configured to allow for separate personnel flow and material flow into the booth.

Case Study #3

An existing fill-finish facility was not properly protecting the stoppered vials between the exit of the class 100 fill room and the exit of the capping operation, where the vials were positively sealed. AES created a custom horizontal laminar flow system that provided ISO 5 conditions around the conveyor line up to and including the capping machine. This product solution combined laminar flow module technology with a custom enclosure that was field-fit onto the production line.